Guidelines Issued for Ketamine Infusions Used for Pain Management

 

As ketamine infusion therapy becomes more popular, many people in the medical community have started to realize they need consensus guidelines for its use. Although ketamine infusions are not FDA approved, they’ve been proven to be an effective treatment for treatment resistant depression, pain management, and other disorder treatment-resistant

 

A panel of experts recently formulated a consensus of guidelines in the use of IV ketamine infusions used to treat chronic pain. The Ketamine Guidelines Committee included representatives from the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. The committee looked at clinical studies and database findings to determine the answers to several questions regarding ketamine infusions.

 

The committee answered the following questions:

 

  1. Which patients and pain conditions should be considered?
  2. What are the contraindications?
  3. Is there any evidence that a therapeutic dose cutoff threshold, a dose-response relationship, longer/more frequent infusions, or higher dosages is more effective?
  4. Is there any role for oral ketamine or another N-methyl-D-aspartate receptor antagonist as a follow-up to infusion?
  5. Should there be pre-infusion testing requirements?
  6. What training should be required for personnel administering and monitoring treatment?
  7. What preemptive medications should be available in case of adverse effects?
  8. What constitutes a positive response in chronic pain?

 

Answers and recommendations were included in response to each question. They came to an overall conclusion that evidence supports the use of ketamine infusions for chronic pain. However, there still needs to be further studies that examine different conditions and dosages. They also concluded that most of the studies already done have been small and uncontrolled. Larger and wider studies still need to be conducted to look at the long term effects of ketamine.

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Dr. Rodriguez founded the Delray Center in 2003 and built it on a foundation of core clinical, professional, and ethical principles that are adhered to still to this day. Dr. Rodriguez founded the Delray Center in 2003 and built it on a foundation of core clinical, professional, and ethical principles that are adhered to still to this day.